Think about all the places you (or members of your household) set down backpacks and other bags when you’re out and about. Over the course of a day, they could come in contact with the floors of bathrooms, buses, or cars, as well as shopping carts, counters, and other people. In other words, they can get pretty gross.

Here’s how to clean backpacks, canvas bags, and other totes without ruining them.

Before washing a backpack or any other bag, check the label for instructions from the manufacturer. Generally speaking, most polyester and nylon bags can be machine-washed (although outdoor retailer REI advises against it ). But while hand-washing may be safest, not everyone has time for that.

Fortunately, there are steps you can take that allow you to machine-wash your backpack without ruining it. These include :

Canvas and cotton totes—like the ones that are probably stuffed in a closet or the trunk of your car right now—can be machine-washed using the same technique described above for backpacks—including air drying them. It’s totally normal for the bags to be pretty wrinkled once they’ve dried. If that bothers you, ironing them will take care of it.

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Backpacks, totes, and other bags made of leather are not machine-washable, but still pretty simple to clean . Start by emptying any pockets and using either a brush or small vacuum attachment to get rid of any dirt, crumbs, or other debris inside.

Then wipe down the outside of the bag with a clean, dry, microfiber cloth. Next, clean the outside of the bag with either a leather-specific cleaner, or a little warm, soapy water. If you opt for soapy water, be sure to towel-dry the bag right away.